Men's weight loss · Oral semaglutide

Medical Weight Loss Pill. No Needles

Oral Wegovy puts semaglutide, the same active ingredient as the weekly injection, into a once-daily tablet. Stored at room temperature. No injections involved.

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HeMed oral weight loss treatment box beside the HeMed app showing verified weight progressOpen HeMed treatment box held in hand, with blister-packed tablets insideTwo HeMed oral weight loss treatment boxes
Round white oral semaglutide tablet
Oral Wegovy® (semaglutide) Once daily · No fridge · No needles · Same active ingredient as the Wegovy injection

16.6%

average body weight lost in the OASIS 4 trial

Sources

Novo Nordisk press release, January 2026: OASIS 4 results, Wegovy pill availability. Trial publication: Wharton S, et al. N Engl J Med 2025;393:1077-1087.

100,000+

Members across the UK

In Partnership With:

HeMed partner logos including Mylo Health, Field Doctor, Vitl and Birmingham City FC

4.8

App Store Rating

The science

The same GLP-1, now in a tablet

Oral Wegovy contains semaglutide, the same active ingredient as the Wegovy injection. It mimics the body's natural GLP-1 hormone and reduces appetite, so people tend to eat less without counting every meal.

Dr Matthew Noble

“Oral semaglutide is the same molecule we have prescribed by injection for years. The delivery changes; the evidence behind it does not.”

Dr Matthew Noble, Chief Medical Officer

Pricing and doses

Four doses, priced plainly

Treatment starts at 1.5mg and steps up to 25mg over roughly 16 weeks. The prescribing clinician sets the pace based on response and side effects. First month from £69 on a 12-month plan.

1.5mgStarting doseWeeks 1 to 4 · Once daily
£154 £69/moFirst month · 12-month plan
4mgTitrationWeeks 4 to 8 · Once daily
£179 £154/mo12-month plan
9mgMid-range doseWeeks 8 to 16 · Once daily
£219 £194/mo12-month plan
25mgMaximum doseWeek 16 onwards · Once daily
£269 £244/mo12-month plan
DoseMonthly3 monthsSave £10/m6 monthsSave £20/m12 monthsSave £25/mFirst month£154£89£79£691.5mg£154£144£134£1294mg£179£169£159£1549mg£219£209£199£19425mg£269£259£249£244

The programme price includes medication, clinical consultations, and HeMed app access. Titration pace varies by person. Savings compare with the rolling monthly price, and first-month pricing applies at the starting dose.

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How it compares

Tablet against injection, in numbers

Tablet

Oral Wegovy

Average loss
16.6%
Needles
None
Routine
Daily tablet
Storage
Room temp

Wegovy inj.

Average loss
28%
Needles
Weekly inj.
Routine
Once weekly
Storage
Fridge

Mounjaro

Average loss
21%
Needles
Weekly inj.
Routine
Once weekly
Storage
Fridge

Individual results vary.

Sources

Novo Nordisk press release, January 2026: OASIS 4 results, Wegovy pill availability. Trial publication: Wharton S, et al. N Engl J Med 2025;393:1077-1087.

Choose The Right Treatment for You

Member voices

Men, in their own words.

Craig, a HeMed member, who lost 19kg in 5 months

“Don't be frightened. I know it's medicine, I know it's a treatment, but for me, it changed my life.

Joining HeMed was the best decision I've made in my life.”

Craig, HeMed member

What to expect

The first months, week by week

Weeks 1 to 4

Getting started

Mild nausea is common while the dose builds. Semaglutide takes four to five weeks to reach a stable level in the body.

Weeks 4 to 12

The appetite effect

Most men start to notice the GLP-1 working. Food noise drops. Side effects from dose increases are usually short-lived.

Week 12 onwards

Settling in

Side effects settle and progress continues with clinical check-ins. Plateaus are a normal part of treatment, not a sign that it has stopped working.

HeMed app in hand showing verified biomarker results for cholesterol, HbA1c and triglycerides

Is it right for you

Who does the daily tablet suit

May suit

BMI 30+, or 27+ with a weight-related condition
Needles are a barrier
Travel often, no fridge access
Can wait 30 minutes after waking before eating
Prefer a daily routine

May not suit

Often forget daily tablets
Rushed mornings
Prefer a once-weekly injection
On Mounjaro and not switching
Cannot wait 30 minutes to eat
Man holding a glass of water at his kitchen counter in the morning, before breakfast Get Started

How it works

The HeMed protocol, in four steps

01Blood test and metabolic profile
02Clinician consultation
03Personalised dose plan
04Ongoing clinical support
Man taking an at-home blood sample with the HeMed test device on his upper arm

Why treatment starts with a blood test: before anything is prescribed, a licensed UK clinician reviews blood sugar, cholesterol, thyroid function, and liver health. That gives a clear metabolic baseline from day one, and a way to measure whether treatment is actually working.

Common questions

Your questions, answered

Oral semaglutide is a once-daily tablet containing semaglutide, a GLP-1 receptor agonist clinically proven to suppress appetite and support sustained weight loss. It delivers the same active ingredient as the Wegovy injection but in tablet form. It is the first oral GLP-1 treatment to receive approval specifically for weight management in the US.

Both treatments use semaglutide as the active ingredient, but the pill is swallowed once daily while the injection is administered once weekly. For men who want to avoid needles entirely, the pill offers the same proven mechanism in a simpler daily format. For best absorption, the tablet should be taken on an empty stomach with a small amount of water, waiting 30 minutes before eating, drinking, or taking other oral medications.

The Wegovy pill targets GLP-1 receptors only, while Mounjaro contains tirzepatide, a dual GIP and GLP-1 receptor agonist that works across two hormonal pathways simultaneously. Mounjaro is currently available in injectable form only, making the Wegovy pill the only needle-free option currently available at HeMed. Your HeMed clinician will recommend the most appropriate treatment based on your health profile and weight loss goals.

Nausea, vomiting, and digestive discomfort are the most commonly reported side effects, consistent with other GLP-1 medications, and typically ease within the first few weeks of treatment. To minimise these, the tablet should be taken on an empty stomach with a small amount of water: wait 30 minutes before eating, drinking, or taking other oral medications. HeMed’s clinical team will monitor your health and support you throughout your treatment.

The Wegovy pill is available in four doses: 1.5mg, 4mg, 9mg, and 25mg. Most men begin on the 1.5mg starting dose and increase gradually under clinical guidance based on their response and tolerance. Your HeMed clinician will determine the right titration schedule for you. Each dose is priced individually, so your monthly price follows your prescribed dose, and plan discounts apply at every dose. The full breakdown is in the pricing table above.

The Wegovy pill is designed for adults with a BMI of 30 or above, or 27+ alongside a weight-related condition such as high blood pressure or type 2 diabetes. It is a strong option for men who want clinically proven weight loss results without weekly injections. A full clinical review is required before prescribing to confirm suitability.

Oral semaglutide has been assessed across large-scale clinical trials and carries a well-established safety profile consistent with injectable semaglutide. Like all prescription weight loss treatments, it requires a full clinical assessment before it can be prescribed. HeMed’s clinicians review your complete health history to ensure the treatment is appropriate for you before you begin.

The Wegovy pill starts from £69 for your first month on a 12-month plan, £79 on a 6-month plan, or £89 on a 3-month plan, with blood tests and clinical support included. After your first month, pricing depends on your dose, starting at £154 a month on a rolling basis, and commitment plans take £10 to £25 off every month. The full dose-by-dose breakdown is shown above, and plan terms, including cancellation, are confirmed at sign-up.

Click Get Started and complete a short eligibility questionnaire. It takes around two minutes. Once confirmed as eligible, you’ll complete an at-home blood test and clinical review before your medication is prescribed and dispatched to your door. No payment or commitment is required until eligibility is confirmed.

Yes. Whether you’re an existing HeMed member or currently with another provider, switching to the Wegovy pill can be discussed with your HeMed clinician. Any switch is assessed on the basis of your current progress, health history, and clinical suitability. Contact your HeMed clinician or our support team to explore your options.

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